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李建科

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    李建科,男,教授(2级),博士生导师,国家现代蜂产业技术体系岗位科学家,中国农业科学院科技创新工程“蜜蜂蛋白质组学” 科研团队首席。曾主持完成国家自然基金,参加“十一五”“十二五”支撑项目,农业行业科研专项等项目。主要从事蜜蜂饲养技术与蜜蜂蛋白质组学研究。近年来 在蛋白质组学国际重要学术期刊,如 《Molecular & Cellular proteomics》,《Journal of Proteome Research》,《Journal of Proteomics》等杂志发表论文30多篇,累积影响因子约170。同时也是Journal of Proteome Research,Journal of Proteomics, BMC Genomics, Apidologie,Insect molecular biology等国际学术期刊的论文评阅人。培养研究生和博士后近30人(其中留学生7人),所指导博士和硕士研究生多名获“国家奖学金”和中国农业科学院优秀博士论文培养对象。
    联系电话:010-62591449;Email: apislijk@126.com

    在研课题:
    [1]中国农业科学院科技创新工程“蜜蜂蛋白质组学”科研团队;
    [2]国家蜂产业技术体系岗位专家。

    Publications: (First and correspondence author listed)
    1.Fan P, Han B, Feng M, Fang Y, Zhang L, Hu H, Hao Y, Qi Y, Zhang X, Li J. Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells. Sci Rep. 2016,6:30230. (IF 5.2)
    2.Hu H, Bienefeld K, Wegener J, Zautke F, Hao Y, Feng M, Han B, Fang Y, Wubie AJ, Li J. Proteome analysis of the hemolymph, mushroom body, and antenna provides novel insight into honeybee resistance against Varroa infestation. J Proteome Res. 2016,15(8): 2841-54. (IF 4.2)
    3.Huo X, Wu B, Feng M, Han B, Fang Y, Hao Y, Meng L, Wubie AJ, Fan P, Hu H, Qi Y, Li J. Proteomic Analysis Reveals the Molecular Underpinnings of Mandibular Gland Development and Lipid Metabolism in Two Lines of Honeybees (Apis mellifera ligustica). J Proteome Res. 2016,15(9):3342-57. (IF 4.2)
    4.Feng M, Fang Y, Han B, Xu X, Fan P, Hao Y, Qi Y, Hu H, Huo X, Meng L, Wu B, Li J. In-Depth N-Glycosylation Reveals Species-Specific Modifications and Functions of the Royal Jelly Protein from Western (Apis mellifera) and Eastern Honeybees (Apis cerana). J Proteome Res. 2015, 14(12):5327-40. (IF 4.23)
    5.Qi Y, Fan P, Hao Y, Han B, Fang Y, Feng M, Cui Z, Li J. Phosphoproteomic Analysis of Protein Phosphorylation Networks in the Hypopharyngeal Gland of Honeybee Workers (Apis mellifera ligustica). J Proteome Res. 2015,14(11):4647-61. (IF 4.23)
    6.Han B, Fang Y, Feng M, Hu H, Qi Y, Huo X, Meng L, Wu B, Li J. Quantitative Neuropeptidome Analysis Reveals Neuropeptides Are Correlated with Social Behavior Regulation of the Honeybee Workers. J Proteome Res. 2015,14(10):4382-93. (IF 4.23)
    7.Fang Y, Feng M, Han B, Qi Y, Hu H, Fan P, Huo X, Meng L, Li J. Proteome Analysis Unravels Mechanism Underling the Embryogenesis of the Honeybee Drone and Its Divergence with the Worker (Apis mellifera lingustica). J Proteome Res. 2015, 14(9):4059-71. (IF 4.23)
    8.Han B, Fang Y, Feng M, Lu X, Huo X, Meng L, Wu B, Li J. In-depth Phosphoproteomic Analysis of Royal Jelly Derived from Western and Eastern Honeybee Species. J Proteome Res. 2014, 13 (12), 5928–5943 (IF 5.1).
    9.Fang Y, Feng M, Han B, Lu X, Ramadan H, Li J. In-depth Proteomics Characterization of Embryogenesis of the Honey Bee Worker (Apis mellifera L.). Mol Cell Proteomics. 2014, 13 (9): 2306-2320. (IF 7.25)
    10.Feng M, Ramadan H, Han B, Fang Y, Li J. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana). BMC Genomics, 2014, 2014, 15:563 (IF 4.4).
    11.Zhang L, Han B, Li R, Lu X, Fang Y, Feng M, Li J. Comprehensive identification of novel proteins and N-glycosylation sites in royal jelly. BMC Genomics, 2014,15:135. (IF 4.4)
    12.Zheng A, Luo J, Meng K, Li J, Zhang S, Li K, Liu G, Cai H, Bryden W, Yao B. Proteome changes underpin improved meat quality and yield of chickens (Gallus gallus) fed the probiotic Enterococcus faecium. BMC Genomics,2014, 15:1167. (IF 4.4)
    13.Li R, Zhang L, Fang Y, Han B, Lu X, Zhou T, Feng M, Li J. Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland. BMC genomics, 2013, 14(1),766. (IF 4.4)
    14.Gala A, Fang Y, Woltedji D, Zhang L, Han B, Feng M, Li J. Changes of Proteome and Phosphoproteome Trigger Embryo-larva Transition of Honeybee Worker (Apis mellifera ligustica). J Proteomics. 2013, 78, 428-46. (IF 4.9)
    15.Han B, Zhang L, Feng M, Fang Y, Li J. An Integrated Proteomics Reveals Pathological Mechanism of Honeybee (Apis cerena) Sacbrood Disease. J Proteome Res. 2013, 12, 1881-97. (IF 5.1)
    16.Woltedji D, Fang Y, Han B, Feng M, Li R, Gala A, Li J. Proteome Analysis of Hemolymph Changes during the Larval to Pupal Development Stages of Honeybee Workers (Apis mellifera ligustica). J Proteome Res. 2013, 12(11), 5189-98. (IF 5.1)
    17.Feng M, Fang Y, Han B, Zhang L, Lu X, Li J. Novel aspects of understanding molecular working mechanisms of salivary glands of worker honeybees (Apis mellifera) investigated by proteomics and phosphoproteomics. J Proteomics. 2013; 87, 1-15. (IF 4.1)
    18.Li H, Zhang L, Ni C,  Shang H,  Zhuang S, Li J. Molecular recognition of floral volatile with two olfactory related proteins in the Eastern honeybee (Apis cerana). Int J Biol Macromol, 2013, 56: 114-21. (IF 2.6)
    19.Begna D, Han B, Feng M, Fang Y, Li J. Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions. J. Proteome Res. 2012, 11 (2), 1317-29. (IF 5.1)
    20.Woltedji D, Song F, Zhang L, Gala A, Han B, Feng M, Fang Y, Li J. Western Honeybee Drones and Workers (Apis mellifera ligustica) Have Different Olfactory Mechanisms than Eastern Honeybees (Apis cerana cerana). J Proteome Res. 2012, 11, 4526-40. (IF 5.1)
    21.Zhang L, Fang Y, Li R, Feng M, Han B, Zhou T, Li J. Towards posttranslational modification proteome of royal jelly. J Proteomics. 2012 ,75, 5327-41. (IF 4.9)
    22.Fang Y, Song F, Zhang L, Woltedji D, Han B, Feng M, Li J. Differential antennal proteome comparison of adult honeybee drone, worker and queen (Apis mellifera L.). J. Proteomics, 2012, 75, 756-73. (IF 4.9)
    23.Begna D, Fang Y, Feng M, Li J. Mitochondrial Proteins Differential Expression during Honeybee (Apis mellifera L.) Queen and Worker Larvae Caste Determination. J. Proteome Res. 2011, 10(9):4263-80. (IF 5.46)
    24.Feng M, Song F, Aleku D, Han B, Fang Y, Li J. Antennal Proteome Comparison of Sexually Mature Drone and Forager Honeybees. J. Proteome Res. 2011, 10(7):3246-60. (IF 5.46)
    25.Zheng A, Li J, Begna D, Fang Y, Feng M, Song F. Proteomic Analysis of Honeybee (Apis mellifera L.) Pupae Head Development. PLoS ONE, 2011, 6(5): e20428. (IF 4.4)
    26.Li J, Fang Y, Zhang L, Begna D. Honeybee (Apis mellifera ligustica) drone embryo proteomes. J. Insect Physiol, 2011, 57 (3), 372-84. (IF 2.31)
    27.Han B, Li C, Zhang L, Fang Y, Feng M, Li J. Novel Royal Jelly Proteins Identified by Gel-Based and Gel-free Proteomics. J. Agric. Food Chem. 2011; 59(18):10346-55. (IF 2.816)
    28.Fang Y, Feng M, Li J. Royal jelly proteome comparison between A. mellifera ligustica and A. cerana cerana. J.Proteome Res. 2010, 9(5):2207-15. (IF 5.132)
    29.Li J, Feng M, Begna D, Fang Y. Proteome comparison of hypopharyngeal gland development between Italian and royal jelly producing worker honeybees (Apis mellifera L.). J. Proteome Res. 2010, 9(12), 6578-94.  (IF 5.132)
    30.Li J, Wu J, Begna D, Song F, Zheng A, Fang Y. Differential Protein Expression in Honeybee (Apis mellifera L.) Larvae: Underlying Caste Differentiation. PLoS ONE, 2010, 5(10): e13455. (IF 4.35)
    31.Feng M, Fang Y, Li J. Proteomic analysis of honeybee worker (Apis mellifera) hypopharyngeal gland development. BMC Genomics. 2009,10: 645. (IF 4.07)
    32.Li J, Zhang L, Feng M, Zhang Z, Pan Y. Identification of the proteome composition occurring during the course of embryonic development of bees (Apis mellifera). Insect Mol Biol., 2009,18 (1): 1-9. (IF 2.787)
    33.Li J, Feng M, Zhang L, Pan Y. Proteomics analysis of major royal jelly protein changes under different storage conditions. J. Proteome Res. 2008, 7 (8), 3339–3353. (IF 5.675)
    34.Li J, Chen J, Zhang Z, Pan Y. Proteome Analysis of Tea Pollen (Camellia sinensis) under Different Storage Conditions. J. Agric. Food Chem. 2008, 56, 7535-44. (IF 2.532)
    35.Li J. Feng M, Zhang Z, Pan Y. Identification of proteome complement of hypopharyngeal gland from two species of worker bees (Apis mellifera). Apidologie. 2008, 39(2): 199-214. (IF 2.2)
    36.Li J. Li H, Zhang Z, Pan Y. Identification of the proteome complement of the higher royal jelly producing bees (Apis mellifera L.) during the worker larvae development. Apidologie, 2007, 38(6): 545-557. (IF 2.2)
    37.Li J. Wang T, Zhang Z, Pan Y. Proteomic Analysis of Royal Jelly from Three Strains of Western Honeybees (Apis  mellifera). J. Agric. Food Chem. 2007, 55, 8411-22. (IF 2.322)


 

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