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Department of Beekeeping Technology and Mechanization

Date:2015-09-21

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Department Name: Department of Beekeeping Technology and Mechanization
Leader: HAN Bin
Brief introduction:
      As a national team of honeybee science inChina, the major goal of the Department of Beekeeping Technology and Mechanization is to develop key technologies and theories that improve the overall performance of our beekeeping industry. At present, the department has an optimized structure of different level of researchers, including one professor, two “Young Talents of CAAS”, one associate professor, four assistant research fellows and one post doctor. Major grants now include the Agricultural Science and Technology Innovation Program (CAAS-ASTIP-2015-IAR), the earmarked fund for Modern Agro-Industry Technology Research System (CARS-45), and the National Natural Science Foundation of China (No. 31501859).
      In recent years, our department has developed dominated advantage in the study of honeybee biology applying proteomics approach, and has made significant contribution to this area and created a significant impact on honeybee science of the globe. Through in-depth study into the biology related to royal jelly production and the function of royal jelly for human health, we have preliminarily revealed the mechanism of how honey bee regulates high production of royal jelly, and identifies the unknown functional components and biological function of royal jelly for the good of human. To date, more than 30 papers have been published in the high rank international academic journals, in which over 20 articles are published in the top international proteomics journals, such as Molecular and Cellular Proteomics, Journal of Proteome Research, Journal of Proteomic. The total impact factor of our published papers is over 150, which accounts for about half of the global total number of the published papers on the bee proteomics in the same period. The research result of "Revealing the mechanism of the high yield and biochemical characteristics of royal jelly" has won the second price of scientific and technological achievements by Beijing committee of science and technology in 2013. In addition, a number of efficient equipment for bee machinery farming the bees has received the inventive or practical patents, which significantly improve the efficiency in beekeeping industry.
     Toward parallel development both in applied and basic research, and the collaborative innovation and training the talented person with other institutes both in China and the globe, our department  will be a center for the developing new beekeeping technologies and the theory innovation of the honeybee biology. As a result, the new beekeeping technologies and the skilled man power will support for the rapid development of beekeeping technologies, theory innovation and talented personal resources of the Chinese beekeeping industry.
Objectives:
     The major goal of our department is to explore and harness the key technologies and theories that improve the overall performance of our beekeeping industry.
1. To reveal the molecular basis of honeybee biology implicated in improving the quality and production of bee-products, and resisting to major pathogens.
2. To deploy resources more efficiently and innovate more collectively, we devote to providing a cooperation platform for both domestic and abroad, and a community for training young talent.
Research Focus:
1. Promoting production efficiency of beekeeping industry by developing new equipment.
2. Revealing the molecular mechanism of the honeybee biology such as royal jelly production using proteomics and gene editing approaches.
3. Functional investigation of royal jelly using glycoproteomics and phosphoproteomics.
Team members:
LI Jianke:
lijianke@caas.cn
HAO Yue: haoyue01@caas.cn
HAN Bin: hanbin@caas.cn
FENG Mao: fengmao@caas.cn
FANG Yu: fangyu@caas.cn
HU Han: huhan@caas.cn
Boris Baer: boris.baer@uwa.edu.au
HUO Xinmei: audeline@sina.com
Awards:
Revealing the mechanism of the high yield and biochemical characteristics of royal jelly won the second price of scientific and technological achievements by Beijing committee of science and technology in 2013
Selected Publications:
1. Bin Han, Yu Fang, Mao Feng, Han Hu, Yuping Qi, Xinmei Huo, Lifeng Meng, Bin Wu, Jianke Li. Quantitative neuropeptidome analysis reveals neuropeptides are correlated with social behavior regulation of the honeybee workers. J Proteome Res. 2015 Aug 27. [Epub ahead of print] (IF 4.25)
2. Yu Fang, Mao Feng, Bin Han, Yuping Qi Y, Han Hu, Pei Fan, Xinmei Huo, Lifeng Meng, Jianke Li. Proteome Analysis Unravels Mechanism Underling the Embryogenesis of the Honeybee Drone and Its Divergence with the Worker (Apis mellifera lingustica). J Proteome Res. 2015 Aug 14. [Epub ahead of print] (IF 4.25)
3. Bin Han, Yu Fang, Mao Feng, Xiaoshan Lu, Xinmei Huo, Lifeng Meng, Bin Wu and Jianke Li. In-depth Phosphoproteomic Analysis of Royal Jelly Derived from Western and Eastern Honeybee Species. J Proteome Res. 2014, 13 (12), 5928–5943 (IF 5.1).
4. Yu Fang, Mao Feng, Bin Han, XiaoShan Lu, Haitham Ramadan, Jianke Li. In-depth Proteomics Characterization of Embryogenesis of the Honey Bee Worker (Apis mellifera L.). Mol Cell Proteomics. 2014, 13 (9): 2306-2320. (IF 7.25)
5. Mao Feng, Haitham Ramadan, Bin Han, Yu Fang and Jianke Li. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana). BMC Genomics, 2014, 2014, 15:563 (IF 4.4).
6. Lan Zhang, Bin Han, Rongli Li, Xiaoshan Lu, Yu Fang, Mao Feng, Jianke Li.. Comprehensive identification of novel proteins and N-glycosylation sites in royal jelly. BMC Genomics, 2014,15:135. (IF 4.4)
7. Aijuan Zheng, Jianjie Luo, Kun Meng, Jianke Li, Shu Zhang, Ke Li, Guohua Liu, Huiyi Cai, Wayne Bryden and Bin Yao. Proteome changes underpin improved meat quality and yield of chickens (Gallus gallus) fed the probiotic Enterococcus faecium. BMC Genomics,2014, 15:1167. (IF 4.4)
8. Rongli Li, Lan Zhang, Yu Fang, Bin Han, Xiaoshan Lu, Tiane Zhou, Mao Feng, Jianke Li. Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland. BMC genomics, 2013, 14(1),766. (IF 4.4)
9. Alemayehu Gala, Yu Fang, Dereje Woltedji, Lan Zhang, Bin Han, Mao Feng, Jianke Li. Changes of Proteome and Phosphoproteome Trigger Embryo-larva Transition of Honeybee Worker (Apis mellifera ligustica). J Proteomics. 2013, 78, 428-46. (IF 4.9)
10. Bin Han, Lan Zhang, Mao Feng, Yu Fang, Jianke Li. An Integrated Proteomics Reveals Pathological Mechanism of Honeybee (Apis cerena) Sacbrood Disease. J Proteome Res. 2013, 12, 1881-97. (IF 5.1)
11. Dereje Woltedji, Yu Fang, Bin Han, Mao Feng, Rongli Li, Alemayehu Gala, Jianke Li. Proteome Analysis of Hemolymph Changes during the Larval to Pupal Development Stages of Honeybee Workers (Apis mellifera ligustica). J Proteome Res. 2013, 12(11), 5189-98. (IF 5.1)
12. Mao Feng, Yu Fang, Bin Han, Lan Zhang, Xiaoshan Lu, Jianke Li. Novel aspects of understanding molecular working mechanisms of salivary glands of worker honeybees (Apis mellifera) investigated by proteomics and phosphoproteomics. J Proteomics. 2013; 87, 1-15. (IF 4.1)
13. Li, HL; Zhang, LY  ; Ni, CX  ; Shang, HW  ; Zhuang, SL  ; Li, JK. Molecular recognition of floral volatile with two olfactory related proteins in the Eastern honeybee (Apis cerana). Int J Biol Macromol, 2013, 56: 114-21. (IF 2.6)
14. Desalegn Begna, Bin Han, Mao Feng, Yu Fang, Jianke Li. Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions. J. Proteome Res. 2012, 11 (2), 1317-29. (IF 5.1)
15. Woltedji Dereje, Song Feifei, Zhang Lan, Alemayehu Gala, Han Bin, Feng Mao, Fang Yu, Jianke Li. Western Honeybee Drones and Workers (Apis mellifera ligustica) Have Different Olfactory Mechanisms than Eastern Honeybees (Apis cerana cerana). J Proteome Res. 2012, 11, 4526-40. (IF 5.1)


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