工作经历:
(1) 2023-08至今,中国农科院蜜蜂研究所,领军人才B类(所级)
(2) 2021-10 至2023-8,重庆大学, 医学院, 教授,博士生导师
(3) 2018-09 至 2021-10, 美国北卡罗来纳大学教堂山分校,
博士后 导师:Aziz Sancar (2015年诺奖获得者)
(3) 2015-04 至 2018-08, 美国内华达大学 博士后 导师:张勇教授
学习经历:
(1) 2009-09 至 2015-01, 中国农业大学, 博士 导师:赵章武教授
(2) 2005-09 至 2009-06, 湖南农业大学, 学士
主持或参加的科研项目:
(1) 2022年国家自然科学基金面上项目,32271211,昼夜节律与核苷酸切除修复相互调控的分子机制研究。2023.01 - 2026.12,本人作用(主持)
(2) 2022年重庆市留学人员回国创业创新支持计划-创新优秀项目,2205012980659430,DNA损伤调控昼夜节律和睡眠的分子神经机制。2023.01-2025.01,本人作用(主持)
(3) 2022年中央高校基本科研业务费项目,2022CDJYGRH-014,外泌体相关LINCRNA介导脓毒症肝损伤的机制及应用研究。2022.09-2025.08,本人作用(联合主持)
(4) NIH Grant, R35 GM118102-01, Molecular Mechanism of Mammalian DNA Excision Repair, DNA Damage Checkpoints and the Circadian Clock, 2016年04月,结题,本人作用(参加)。
(5) NIH Grant, R01 ES027255-02, Single Nucleotide Resolution Map of Formation and Repair of Bulky Adducts in the Human Genome, 2016年06月,在研,本人作用(参加)。
(6) NIH Grant, P20 GM103650, The Role of DOMINO in Regulation of Circadian Rhythms in Drosophila, 2017年07月,结题,本人作用(参加)。
参加国内外会议:
(1)2023年4月,中国细胞生物学学会 2022年全国学术大会·苏州,大会报告,报告题目:衰老与生物节律偶 联对核酸切除修复的影响及机制研究。
(2) 2022年4月至6月,作为特邀嘉宾多次参加中国细胞生物学学会生物节律分会“云生物钟”论坛。
(3) 2020年Participation 2020 SRBR Meeting. UAS. On Line.
(4) 2017年Regulation of sleep by IMP in Drosophila melanogaster. Poster presentation: The 58th Annual Drosophila Research Conference. San Diego.
(5) 2011年Conference abstract of The Third International Symposium on Insect Physiology, Biochemistry and Molecular Biology. Shanghai, China.
代表性论文:(#第一作者,*通讯作者)
(1) Li H#, Zhang H#, Ding K, Wang X, Sun G*, Liu Z*, Luo Y*. The evolving epidemiology of monkeypox virus. Cytokine & Growth Factor Reviews. 2022 October 8; Volume 68 Pages 1-12.
(2) Liu Z#, Xiao M#, Mo Y, Wang H, Han Y, Zhao X, Yang X, Liu Z, Xu B*. Emerging roles of protein palmitoylation and its modifying enzymes in cancer cell signal transduction and cancer therapy. Int J Biol Sci. 2022 May 9;18(8):3447-3457.
(3) Deger, N.#, Cao, X.#, Selby, C.P., Gulec, S., Kawara, H., Dewey, E.B., Wang, L., Yang, Y., Archibald, S., Selcuk, B., Adebali O, Sekelsky J, Sancar, A.*, Liu, Z.* (2022). CSB-independent, XPC-dependent transcription-coupled repair in Drosophila. PNAS. 119. No. 9 e2123163119.
(4) Liu, Z., Selby, C.P., Yang, Y., Lindsey-Boltz, L.A., Cao, X., Eynullazada, K., and Sancar, A. (2020). Circadian regulation of c-MYC in mice. PNAS. 117, 21609- 21617.
(5) Liu, Z., Tabuloc, C.A., Xue, Y., Cai, Y., McIntire, P., Niu, Y., Lam, V.H., Chiu, J.C., and Zhang, Y. (2019). Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance. PLoS Genetics. 15, e1008474.
(6) Chen, W. #, Liu, Z. #, Li, T., Zhang, R., Xue, Y., Zhong, Y., Bai, W., Zhou, D., and Zhao, Z. (2014). Regulation of Drosophila circadian rhythms by miRNA let-7 is mediated by a regulatory cycle. Nature communications. 5, 5549.
(7) Niu, Y., Liu, Z., Nian, X., Xu, X., and Zhang, Y. (2019). miR-210 controls the evening phase of circadian locomotor rhythms through repression of Fasciclin 2. PLoS Genetics.15, e1007655.
(8) Yang, Y., Liu, Z., Selby, C.P., and Sancar, A. (2019). Long-term, genome-wide kinetic analysis of the effect of the circadian clock and transcription on the repair of cisplatin-DNA adducts in the mouse liver. JBC. 294, 11960-11968.
(9) Cao, X., Yang, Y., Selby, C.P., Liu, Z. , Sancar, A. (2020) Molecular mechanism of the repressive phase of the mammalian circadian clock. PNAS. 118(2): e2021174118.
(10) Yang, Y., Lindsey-Boltz, L.A., M Vaughn, C., Selby, C.P., Cao, X., Liu, Z., S Hsu, D. and Sancar, A. (2021). Circadian clock, carcinogenesis, chronochemotherapy connections. JBC. 297, 3.
(11) Cong, X., Wang H., Liu, Z. , He C., An, C., Zhao, Z.Regulation o f Sleep by Insulin-like Peptide System in Drosophila melanogaster, Sleep, 2014, 38(7): 1075-U89.
(12) Liu, Z. , Zhao, Z.Effects of Light Interruption on Sleep and Viability of Drosophila melanogaster, PLOS ONE, 2014, 9(8): 1-11
期刊编委
(1) Review Editor for: PLOS Genetics, Chronobiology International, Frontiers in Genetics, Frontiers in Toxicology, Frontiers in Neuroscience, Sleep Advances.
(2)Ad hoc Reviewer for: BMC Neuroscience, Frontiers in Environmental Science etc.