科研团队

代表性科研成果

1. 【获奖成果】

1、2017年，优质蜂产品安全生产加工与质量控制技术，国务院，国家技术发明奖二等奖，第1完成人

2、2016年，蜂蜜优质安全生产全程控制与增值加工新技术及推广应用，农业部，全国农牧渔业丰收奖一等奖，第1完成人

3、2015年，蜂王浆优质高效生产和质量安全评价新技术研究与应用，农业部，中国农业科技奖一等奖，第1完成人

4、2017年，蜜蜂健康高效养殖和蜂产品深加工技术创新与应用，河南省人民政府，河南省科学技术进步奖二等奖，第2完成人

2. 【代表性论文清单】

1. Yan, S.; Wang, K.; Al Naggar, Y.; Vander Heyden, Y.; Zhao, L.; Wu, L.; Xue, X., Natural plant toxins in honey: An ignored threat to human health. Journal of Hazardous Materials 2022, 424: 127682. 10.588.

2. El-Wahed AAA, Khalifa SAM, Elashal MH, Musharraf SG, Saeed A, Khatib A, Tahir HE, Zou X, Naggar YA, Mehmood A, Wang K, El-Seedi HR (2021) Cosmetic Applications of Bee Venom. Toxins 13: 810. 4.546.

3. El Kholy S, Wang K, El-Seedi HR, Al Naggar Y (2021) Dopamine Modulates Drosophila Gut Physiology, Providing New Insights for Future Gastrointestinal Pharmacotherapy. Biology 10: 983. 5.079.

4. Zhang WW#, Qi SZ, Xue XF, Al Naggar Y, Wu LM*, Wang K* (2021) Understanding the Gastrointestinal Protective Effects of Polyphenols using Foodomics-Based Approaches. Frontiers in Immunology 12. 7.561.

5. Guo N#, Zhao L#, Zhao Y, Li Q, Xue X, Wu L, Gomez Escalada M, Wang K*, Peng W* (2020) Comparison of the Chemical Composition and Biological Activity of Mature and Immature Honey: An HPLC/QTOF/MS-Based Metabolomic Approach. Journal of Agricultural and Food Chemistry 68: 4062-4071. 5.279.

6. Sun L-P#, Shi F-F, Zhang W-W, Zhang Z-H, Wang K* (2020) Antioxidant and Anti-Inflammatory Activities of Safflower (Carthamus tinctorius L.) Honey Extract. Foods 9: 1039. 4.35.

7. Wang K, Wan Z, Ou A, Liang X, Guo X, Zhang Z, Wu L, Xue X (2019) Monofloral honey from a medical plant, Prunella Vulgaris, protected against dextran sulfate sodium-induced ulcerative colitis via modulating gut microbial populations in rats. Food & function 10: 3828-3838. 5.396

8. Hu L, Wu C, Zhang Z, Liu M, Prasad EM, Chen Y, Wang K (2019) Pinocembrin Protects Against Dextran Sulfate Sodium-induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota. Frontiers in Physiology 10. 4.566.

9. Wang K, Conlon M, Ren W, Chen BB, Bączek T (2018) Natural Products as Targeted Modulators of the Immune System. Journal of Immunology Research 2018: Article ID 7862782, 2 pages. 4.818.

10. Zhao, L.; Ren, C.; Xue, X.; Lu, H., Wang, K.; Wu, L. Safflomin A: A novel chemical marker for Carthamus tinctorius L. (Safflower) monofloral honey, Food Chemistry, 2022, 366:130584. 7.514.

11. Xiaorong Sun; Xiaofeng Xue; Xiaqing Wang; Chun Zhang; Dengyu Zheng; Song Wei; Jiuran Zhao; Jianhua Wei; Zhongyi Wu; Zhongbao Zhang. Natural variation of ZmCGT1 is responsible for isoorientin accumulation in maize silk. The plant journal, 2022, 109(1):64-76.

12. Yin, S.; Tao, Y.; Jiang, Y.; Meng, L.; Zhao, L.; Xue, X.; Li, Q.; Wu, L. A combined proteomic and metabolomic strategy for allergens characterization in natural and fermented Brassica napus bee pollen. Frontiers in Nutrition, 2022, 9, 822033. 6.582.

13. Mu, X. Y.; Qi, S. Z.; Liu, J.; Wang, H.; Yuan, L. L.; Qian, L.; Li, T. J.; Huang, Y.; Wang, C. J.; Guo, Y. M.; Li, Y. R., Environmental level of bisphenol F induced reproductive toxicity toward zebrafish. Science of the Total Environment, 2022, 806. 8.071.

14. Mu, X. Y.; Qi, S. Z.; Liu, J.; Yuan, L. L.; Huang, Y.; Xue, J. Y.; Qian, L.; Wang, C. J.; Li, Y. R., Toxicity and behavioral response of zebrafish exposed to combined microplastic and bisphenol analogues. Environmental Chemistry Letters, 2022, 20:41-48. 9.027.

15. Li, Q.; Ren, C.; Yan, S.; Wang, K.; Hrynets, Y.; Xiang, L.; Xue, X.; Betti, M.; Wu, L. Extract of unifloral Camellia sinensis L. pollen collected by Apis mellifera L. honeybees exerted inhibitory effects on glucose uptake and transport by interacting with glucose transporters in human intestinal cells. Journal of Agricultural and Food Chemistry, 2021, 69(6), 1877-1887. 5.279.

16. Wang, M.; Xiao, Y.; Li, Y.; Wang, X.; Qi, S.; Wang, Y.; Zhao, L.; Wang, K.; Peng, W.; Luo, G.; Jia, G.; Xue, X.; Wu, L. RNA m6A Modification Functions in Larval Development and Caste Differentiation in Honeybee (Apis mellifera). Cell Reports 2021, 34(1): 108580. 9.423.

17. Wang, M.; Chen, D.; Zheng, H.; Zhao, L.; Xue, X.; Yu, F.; Zhang, Yu; Cheng, C.; Niu, Q.; Wang, S., Zhang Yi; Wu, L. Sex-Specific Development in Haplodiploid Honeybee Is Controlled by the Female-Embryo-Specific Activation of Thousands of Intronic LncRNAs. Frontiers in Cell and Developmental Biology 2021, 9: 690167. 6.684.

18. Li, J. H.; Zhao, L. W.; Qi, S. Z.; Zhao, W. T.; Xue, X. F.; Wu, L. M.; Huang, S. K., Sublethal effects of Isoclast(TM) Active (50% sulfoxaflor water dispersible granules) on larval and adult worker honey bees (Apis mellifera L.). Ecotoxicology and Environmental Safety, 2021, 220: 112379. 6.291.

19. Liu, Y. Y.; Wang, C.; Qi, S. Z.; He, J.; Bai, Y. C., The sublethal effects of ethiprole on the development, defense mechanisms, and immune pathways of honeybees (Apis melliferaL.). Environmental Geochemistry and Health 2021, 43, (1), 461-473. 4.609.

20. Wang, K.; Li, J. H.; Zhao, L. W.; Mu, X. Y.; Wang, C.; Wang, M.; Xue, X. F.; Qi, S. Z.; Wu, L. M., Gut microbiota protects honey bees ( Apis mellifera L.) against polystyrene microplastics exposure risks. Journal of Hazardous Materials, 2021, 402:123828. 10.588.

21. Meijie Song ; Kai Wang ; Huanxian Lu ; Sha Yan ; Liming Wu ;* Xiaofeng Xue*. Composition and distribution of α-dicarbonyl compounds in propolis from different plant origins and extraction processing. Journal of Food Composition and Analysis 2021, 104:104141. 4.556.

22. Yan, S.; Song, M. J.; Wang, K.; Fang, X. M.; Peng, W. J.; Wu, L. M.; Xue, X. F., Detection of acacia honey adulteration with high fructose corn syrup through determination of targeted alpha-Dicarbonyl compound using ion mobility-mass spectrometry coupled with UHPLC-MS/MS. Food Chemistry 2021, 352:129312. 7.514.

23. Yan, S.; Wang, K.; Wang, X. Y.; Ou, A. Q.; Wang, F. R.; Wu, L. M.; Xue, X. F., Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice. Food Science and Human Wellness 2021, 10 (3):345-355. 5.154.

24. Li, Q.; Liang, X.; Xue, X.; Wang, K.; Wu, L. Lipidomics provides novel insights into understanding the bee pollen lipids transepithelial transport and metabolism in human intestinal cells. Journal of Agricultural and Food Chemistry, 2020, 68, 907-917. 5.279.

25. Qi, S. Z.; Niu, X. Y.; Wang, D. H.; Wang, C.; Zhu, L. Z.; Xue, X. F.; Zhang, Z. Y.; Wu, L. M., Flumethrin at sublethal concentrations induces stresses in adult honey bees (Apis mellifera L.). Science of the Total Environment, 2020, 700: 134500. 7.963.

26. Qi, S. Z.; Zhu, L. Z.; Wang, D. H.; Wang, C.; Chen, X. F.; Xue, X. F.; Wu, L. M., Flumethrin at honey-relevant levels induces physiological stresses to honey bee larvae (Apis mellifera L.) in vitro. Ecotoxicology and Environmental Safety, 2020, 190:110101. 6.291.

27. Zhu, L. Z.; Qi, S. Z.; Xue, X. F.; Niu, X. Y.; Wu, L. M., Nitenpyram disturbs gut microbiota and influences metabolic homeostasis and immunity in honey bee (Apis mellifera L.). Environmental Pollution, 2020, 258:113671. 8.071.

28. Wang, M.; Li, H.; Zheng H.; Zhao L.; Xue, X.; Wu, L. De novo transcriptomic resources in the brain of Vespa velutina for invasion control, Insects 2020, 11, 101. 2.769.

29. Guo, N.; Zhao, L.; Zhao, Y.; Li Q.; Xue, X.; Wu, L.; Escalada, M.; Wang, K.; Peng, W. Comparison of the Chemical Composition and Biological Activity of Mature and Immature Honey: An HPLC/QTOF/MS-Based Metabolomic Approach, Journal of Agricultural and Food Chemistry, 2020, 68: 4062−4071. 5.279.

30. 宋美洁，欧爱群，薛晓锋，吴黎明，寿旗扬，王凯*. 蜂胶提取物对脂多糖诱导小鼠急性乳腺炎及乳腺屏障功能的保护作用. 中国农业科学, 2021, 54（12）：2675-2688.

31. 宋美洁，吴翠玲，赵柳微，吴黎明，卢焕仙，薛晓锋. QuEChERS 结合超高效液相色谱串联质谱法同时测定蜂蜜和蜂王浆中红霉素及其降解物残留量.食品与发酵工业, 2021, 47(22), 254-259.

32. 赵彤, 赵洪木, 宋美洁, 杜伟, 吴黎明, 范芳芳，薛晓锋. 超高效液相色谱-串联质谱法测定蜂王幼虫中烟酰胺单核苷酸的含量. 食品与发酵工业, 2021.网络首发.

33. 赵彤，王宣，吴黎明，延莎，卢焕仙，赵洪木，薛晓锋. 发酵蜂产品研究进展.食品工业科技, 2021，中国（广西梧州）蜂业博览会暨全国蜂产品市场信息交流会论文集（上册），308-315.

34. 尹舒婷; 姜玉锁; 李强强; 吴黎明. 蜂花粉过敏原识别及微生物发酵法降解过敏原的潜在应用研究进展; 食品工业科技, DOI: 10.13386/j.issn1002-0306.2021060122.

35. 李佳欢; 齐素贞; 吴黎明; 黄少康. 氟虫腈对意大利蜜蜂工蜂幼虫及幼龄工蜂的亚致死效应研究; 生态毒理学报, 2021, 16(5): 314-325.

36. 郑星; 王凯; 薛晓锋; 汪正威; 潘鹏; 吴黎明; 赵亚周; 彭文君.高效液相色谱-示差折光检测法检测无刺蜂蜂蜜中海藻酮糖含量[J/OL].食品科学:1-14[2021-08-25.

37. 宋美洁; 欧爱群; 薛晓锋; 吴黎明; 寿旗扬; 王凯. 蜂胶提取物对脂多糖诱导小鼠急性乳腺炎及乳腺屏障功能的保护作用[J].中国农业科学,2021,54(12):2675-2688.

38. 郑星; 梁馨文; 吴黎明; 薛晓锋; 汪正威; 王凯; 彭文君.无刺蜂蜂蜜研究进展[J/OL].食品工业科技:1-12[2021-08-25.

39. 任彩君; 吴黎明; 王凯.膳食多酚对肠道菌群影响研究进展[J/OL].食品工业科技:1-17.

40. 郭娜娜; 赵亚周; 王凯; 彭文君.蜂蜜对创伤愈合的作用及机理研究进展[J].中国农业科技导报,2021,23(02):123-133.

41. 欧爱群;赵必安;李江红;王凯;彭文君.蜂胶防治奶牛乳腺炎研究进展[J].畜牧与兽医,2020,52(03):145-150.

3.【团队专利清单】

1. 薛晓锋, 方小明, 吴黎明, 彭文君, 田文礼, 王凯. 蜂蜜花粉丸制备装置.专利号ZL 202022433414.7, 授权公告日：2021.01.26.

2. 薛晓锋，延莎，任彩君，王宣，田文礼，赵红木，卢焕仙，王凯，吴黎明，赵柳微. 氨基酸对苯醌类化合物及其作为米团花黑色蜂蜜特征性标志物的应用. 专利号ZL202110725017.3, 授权公告日: 2021.08.13.

3. 王凯，吴黎明，梁馨文，薛晓锋. 一种夏枯草蜂蜜的鉴别方法，专利号ZL201810643017.7，授权公告日：2021.06.27.

4. 李强强, 陶宇逍, 尹舒婷, 吴黎明, 薛晓峰, 王妙. 一种评价天然蜂花粉与酶法破壁蜂花粉致敏性的方法. 专利号 ZL 202110894683.X, 授权公告日：2021.10.22.

5. 李强强, 吴黎明, 薛晓峰, 陶宇逍, 尹舒婷. 一种蜂花粉致敏蛋白的鉴定方法及应用. 专利号 ZL 202110732923.6, 授权公告日：2021.11.16.

6. 李强强, 吴黎明, 陶宇逍, 尹舒婷, 薛晓锋, 赵柳微. 一种评估天然蜂花粉及发酵蜂花粉致敏性的方法. 专利号 ZL 202110733122.1, 授权公告日：2021.11.19.

7. 吴黎明，齐素贞，王妙，赵柳微，薛晓锋，王凯. 一种蜂用缓释型过氧乙酸消毒剂及其制备方法和应用，专利号ZL201911176808.4，授权日期2021.12.07.

8. 赵柳微，梁馨文，吴黎明，薛晓锋，万正瑞. 一种蜂花粉中农药残留的检测方法, 专利号 ZL2018103730057，授权公告日：2021.06.18.

9. 赵柳微，任彩君，王凯，吴黎明，薛晓锋. 三叶豆苷作为胡枝子蜜特征性标志物的应用，专利号ZL20210310477X，授权公告日：2021.06.18.

10. 齐素贞，吴黎明，薛晓锋，王凯，牛新月.一种检测农药对蜜蜂胚胎发育影响的试验方法，专利号ZL201810531729.X，授权日期2020.05.19.

11. 齐素贞，吴黎明，薛晓锋，王凯，牛新月.一种测定农药对蜜蜂幼虫发育影响的试验方法，专利号 ZL201810530687.8，授权日期2020.06.09.

12. 赵柳微，吴黎明，薛晓锋，王妙，王凯，齐素贞. 一种β-环糊精负载过氧化氢的缓释型消毒盒, 专利号ZL201821999383.8，授权公告日：2020.01.14.

13. 薛晓锋, 孙明辉, 吴黎明, 尹旭升, 刘新迎, 王凯, 赵玲玲. 一种快速识别蜂蜜品种和掺假蜂蜜的方法. 专利号ZL201810462442.6，授权公告日：2018.10.12.

14. 王凯，吴黎明，梁馨文，薛晓锋.一种无刺蜂蜂蜜提取物及其提取方法和应用，专利号ZL201810750208.3，授权公告日：2019.07.18.

15. 王凯，梁馨文，王亮，吴黎明，薛晓锋. 无刺蜂蜂蜜多酚物质的提取及其在免疫调节中的应用，专利号ZL201710696882.3，授权公告日：2019.06.21.

16. 王凯，李强强，吴黎明，薛晓锋. 一种快速分析蜂花粉中脂类成分的方法，专利号ZL201710415148.5，授权公告日：2020.03.21.

17. 王凯，吴黎明，薛晓锋. 一种宠物用牙膏及其制备方法，专利号ZL201710675356.9, 授权公告日：2020.03.1.

4. 【著作清单】

蜂王浆品质评价新方法及应用、中国农业科学技术出版社、吴黎明//薛晓锋//胡福良//郑火青、2019-10-01