个人简介
王凯，1988年6月生，安徽芜湖人，博士，副研究员，硕士生导师，国家自然科学基金优秀青年科学基金获得者（2023年）、北京市科技新星（2022年）。2016年博士毕业于浙江大学动物科学学院，2016年7月至今就职于中国农业科学院蜜蜂研究所，现为中国农业科学院蜜蜂研究所蜂产品质量与风险评估创新团队科研骨干，主要研究方向为蜜蜂及蜂产品学。先后主持国家自然科学基金优秀青年科学基金、面上项目、青年基金、中央级公益性科研院所基本科研业务费专项等课题。近五年在国内外重要刊物上发表论文60余篇，其中近五年以第一/通讯作者发表SCI论文28篇（其中IF>10.0论文三篇），ESI高被引论文3篇，中文第一/通讯作者论文8篇，H指数32，论文总被引次数超过2500次，入选斯坦福大学全球前2%顶尖科学家“年度影响力”榜单（2022年度）。兼任Frontiers in Nutrition等SCI期刊副主编、BMC Complementary Medicine and Therapies、PLoS One等SCI期刊编委，担任Comprehensive Reviews in Food Science and Food Safety等多本SCI杂志审稿人。以第一发明人获国家发明专利授权9项、独立译著1部（58万字）、副主编、参编著作3部。
Email: kaiwang628@gmail.com; wangkai@caas.cn
教育经历
2011-2016 浙江大学 动物科学学院 博士
2015-2016 澳大利亚联邦科工组织 食品营养研究所 博士联合培养
2007-2011 湖南农业大学 动物科学技术学院 学士
工作经历
2019 至今 中国农业科学院蜜蜂研究所 副研究员
2016-2018 中国农业科学院蜜蜂研究所 助理研究员
研究领域
蜜蜂及蜂产品学
科研项目
1. 国家自然科学基金优秀青年科学基金项目，蜜蜂及蜂产品学，批准号32322079，200万元，2024.01- 2026.12，主持，在研
国家自然科学基金面上项目，蜂胶通过肠道共生菌动态调控西方蜜蜂免疫反应作用研究，批准号32172791，58万元，2022.01- 2025.12，主持，在研
2. 北京市科技新星计划-创新新星，北京市科学技术委员会、中关村科技园区管理委员会，批准号：20220484101，40万元，2022.10-2025.10，主持，在研
3. 中国农业科学院“青年创新专项”任务，基于信息素传导/肠道微生物途径研究蜂胶对蜜蜂蜂群稳态的作用机制，批准号Y2022QC09，150万元，主持，在研
4. 质兰公益基金会一般项目；西藏墨脱地区野生无刺蜂的资源调查和可持续利用；2022040591B；2022年7月1日至2023年6月30日；13.196万元，主持，在研
5. 国家自然科学基金青年科学基金项目，蜂胶调控紧密连接蛋白对奶牛乳腺上皮细胞炎性损伤的保护机制，批准号31702287，24万元，2018.01- 2020.12，主持，已结题
成果奖励
1. 山东省高等学校科学技术奖，本科科学技术类一等奖（第三完成人），山东省教育厅，2016.12
国内外学术组织及重要学术期刊任职情况
1. Frontiers in Nutrition，副主编，2021-至今
2. Frontiers in Veterinary Science，副主编，2022-至今
3. BMC Complementary Medicine and Therapies，编 委，2019-至今
4. Nutrients，编 委，2023-至今
5. PLoS One，编 委，2022-至今
6. Journal of Food Biochemistry，编 委，2022-至今
7. 中国营养学会营养与保健食品分会第五届委员会委员，2021年-2025年
科研论文及著作
1. Zheng X#, Pan F#, Naumovski N, Wei Y, Wu L, Peng W*, Wang K* (2023) Precise prediction of metabolites patterns using machine learning approaches in distinguishing honey and sugar diets fed to mice. Food Chem 430: 136915
2. Baky MH#, Abouelela MB, Wang K*, Farag MA*(2023) Bee Pollen and Bread as a Super-Food: A Comparative Review of Their Metabolome Composition and Quality Assessment in the Context of Best Recovery Conditions. Molecules 28
3. Zheng X#, Al Naggar Y#, Wu Y, Liu D, Hu Y, Wang K*, Jin X*, Peng W* (2023) Untargeted metabolomics description of propolis's in vitro antibacterial mechanisms against Clostridium perfringens. Food Chem 406: 135061
4. Algethami JS#, El-Wahed AAA, Elashal MH, Ahmed HR, Elshafiey EH, Omar EM, Naggar YA, Algethami AF, Shou Q, Alsharif SM, Xu B, Shehata AA, Guo Z, Khalifa SAM, Wang K*, El-Seedi HR* (2022) Bee Pollen: Clinical Trials and Patent Applications. Nutrients 14
5. El-Seedi HR#,*, Ahmed HR, El-Wahed AAA, Saeed A, Algethami AF, Attia NF, Guo Z, Musharraf SG, Khatib A, Alsharif SM, Naggar YA, Khalifa SAM, Wang K* (2022) Bee Stressors from an Immunological Perspective and Strategies to Improve Bee Health. Veterinary Sciences 9
6. El-Seedi HR#,*, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, Zhao C, Al Naggar Y, Alsharif SM, Tahir HE, Xu BJ, Wang K*, Khalifa SAM (2022) Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties. Front Nutr 8
7. Jiang Q#, Charoensiddhi S, Xue X, Sun B, Liu Y, El-Seedi HR, Wang K* (2022) A review on the gastrointestinal protective effects of tropical fruit polyphenols. Crit Rev Food Sci Nutr: 1-27
8. Li Q#, Chen G, Zhu D, Zhang W, Qi S, Xue X, Wang K*, Wu L (2022) Effects of dietary phosphatidylcholine and sphingomyelin on DSS-induced colitis by regulating metabolism and gut microbiota in mice. The Journal of Nutritional Biochemistry 105: 109004
9. Qi S#, Al Naggar Y#, Li J, Liu Z, Xue X, Wu L, El-Seedi HR, Wang K* (2022) Acaricide flumethrin-induced sublethal risks in honeybees are associated with gut symbiotic bacterium Gilliamella apicola through microbe-host metabolic interactions. Chemosphere 307: 136030
10. Yan S#, Wang K*, Al Naggar Y, Vander Heyden Y, Zhao L, Wu L, Xue X (2022) Natural plant toxins in honey: An ignored threat to human health. Journal of Hazardous Materials 424: 127682
11. Zhang W#, Margarita GE, Wu D, Yuan W, Yan S, Qi S, Xue X, Wang K*, Wu L* (2022) Antibacterial Activity of Chinese Red Propolis against Staphylococcus aureus and MRSA. Molecules 27
12. Zheng X#, Zhao Y#, Naumovski N, Zhao W, Yang G, Xue X, Wu L, Granato D*, Peng W*, Wang K* (2022) Systems Biology Approaches for Understanding Metabolic Differences Using 'Multi-Omics' Profiling of Metabolites in Mice Fed with Honey and Mixed Sugars. Nutrients 14: 3445
13. Zhao L#, Ren C#, Xue X, Lu H, Wang K*, Wu L* (2022) Safflomin A: A novel chemical marker for Carthamus tinctorius L. (Safflower) monofloral honey. Food Chemistry 366: 130584
14. Wang K#, Li J, Zhao L, Mu X, Wang C, Wang M, Xue X, Qi S*, Wu L* (2021) Gut microbiota protects honey bees (Apis mellifera L.) against polystyrene microplastics exposure risks. Journal of Hazardous Materials 402: 123828 (IF= 10.588)
15. Zhang WW#, Qi SZ, Xue XF, Al Naggar Y, Wu LM*, Wang K* (2021) Understanding the Gastrointestinal Protective Effects of Polyphenols using Foodomics-Based Approaches. Frontiers in Immunology 12 (IF= 7.561)
16. El Kholy S#, Wang K*, El-Seedi HR, Al Naggar Y* (2021) Dopamine Modulates Drosophila Gut Physiology, Providing New Insights for Future Gastrointestinal Pharmacotherapy. Biology-Basel 10 5.079
17. Abd El-Wahed AA#, Khalifa SAM, Elashal MH, Musharraf SG, Saeed A, Khatib A, Tahir HE, Zou XB, Al Naggar Y, Mehmood A, Wang K*, El-Seedi HR* (2021) Cosmetic Applications of Bee Venom. Toxins 13
18. Guo N#, Zhao L#, Zhao Y, Li Q, Xue X, Wu L, Gomez Escalada M, Wang K*, Peng W* (2020) Comparison of the Chemical Composition and Biological Activity of Mature and Immature Honey: An HPLC/QTOF/MS-Based Metabolomic Approach. Journal of Agricultural and Food Chemistry 68: 4062-4071 (IF= 5.279)
19. Li Q#, Liang X, Xue X, Wang K*, Wu L* (2020) Lipidomics Provides Novel Insights into Understanding the Bee Pollen Lipids Transepithelial Transport and Metabolism in Human Intestinal Cells. Journal of Agricultural and Food Chemistry 63: 907-917
20. Sun L-P#, Shi F-F, Zhang W-W, Zhang Z-H, Wang K* (2020) Antioxidant and Anti-Inflammatory Activities of Safflower (Carthamus tinctorius L.) Honey Extract. Foods 9: 1039
21. Wang K#,*, Wan Z, Ou A, Liang X, Guo X, Zhang Z, Wu L*, Xue X* (2019) Monofloral honey from a medical plant, Prunella Vulgaris, protected against dextran sulfate sodium-induced ulcerative colitis via modulating gut microbial populations in rats. Food & function 10: 3828-3838 (IF= 5.396)
22. Hu L#, Wu C, Zhang Z, Liu M, Prasad EM, Chen Y*, Wang K* (2019) Pinocembrin Protects Against Dextran Sulfate Sodium-induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota. Frontiers in Physiology 10 (IF= 4.566)
23. Li Q#, Liang X, Guo N, Hu L, Wu Y, Xue X, Wu L*, Wang K* (2019) Protective effects of Bee pollen extract on the Caco-2 intestinal barrier dysfunctions induced by dextran sulfate sodium. Biomedicine & Pharmacotherapy 117: 109200 (IF= 6.529)
24. Li Q#, Sun M, Wan Z, Liang J, Betti M, Hrynets Y, Xue X, Wu L, Wang K* (2019) Bee Pollen Extracts Modulate Serum Metabolism in Lipopolysaccharide-induced Acute Lung Injury Mice with Anti-inflammatory Effects. Journal of Agricultural & Food Chemistry 67: 7855-7868 Journal of Agricultural and Food Chemistry 68: 4062-4071
25. Wang K#,*, Conlon M, Ren W, Chen BB, Bączek T (2018) Natural Products as Targeted Modulators of the Immune System. Journal of Immunology Research 2018: Article ID 7862782, 2 pages
26. Wang K#, Jin X, Li Q, Sawaya ACHF, Le Leu RK, Conlon MA, Wu L*, Hu F* (2018) Propolis from Different Geographic Origins Decreases Intestinal Inflammation and Bacteroides spp. Populations in a Model of DSS-Induced Colitis. Molecular Nutrition & Food Research 62: 1800080
27. Wang K#, Yang Q#, Ma Q, Wang B, Wan Z, Chen M, Wu L* (2018) Protective effects of salvianolic acid a against dextran sodium sulfate-induced acute colitis in rats. Nutrients 10
28. Li Q#, Wang K*, Marcucci MC, Sawaya ACHF, Hu L, Xue X-F, Wu L-M*, Hu F-L (2018) Nutrient-rich bee pollen: a treasure trove of active natural metabolites. Journal of Functional Foods 49: 472-484
近五年代表性中文论文（*通讯作者）：
1. 袁文芹,玄红专,王凯*.蜂蜜中抗菌活性物质及其抑菌作用机理研究进展[J].食品工业科技,2023,44(04):438-446.
2. 郑星,王凯*,薛晓锋,汪正威,潘鹏,吴黎明,赵亚周,彭文君*.高效液相色谱-示差折光检测法检测无刺蜂蜂蜜中海藻酮糖含量[J].食品科学,2022,43(16):217-225.
3. 宋美洁,欧爱群,薛晓锋,吴黎明,寿旗扬,王凯*.蜂胶提取物对脂多糖诱导小鼠急性乳腺炎及乳腺屏障功能的保护作用[J].中国农业科学,2021,54(12):2675-2688.
4. 郑星,梁馨文,吴黎明,薛晓锋,汪正威,王凯*,彭文君.无刺蜂蜂蜜研究进展[J].食品工业科技,2022,43(01):458-465.
5. 任彩君,吴黎明,王凯*.膳食多酚对肠道菌群影响研究进展[J]. 食品工业科技,2022,43(01):400-409.
6. 郭娜娜,赵亚周,王凯*,彭文君*.蜂蜜对创伤愈合的作用及机理研究进展[J].中国农业科技导报,2021,23(02):123-133.
7. 欧爱群,赵必安,李江红,王凯*,彭文君.蜂胶防治奶牛乳腺炎研究进展[J].畜牧与兽医,2020,52(03):145-150.
8. 常化松,袁雯雯,玄红专,王凯*.黄酮类化合物吸收代谢及其对胃肠道功能影响的研究进展[J].食品工业科技,2019,40(18):340-347.
9. 王蓓,常化松,苏松坤,孙丽萍,王凯*.无刺蜂蜂胶乙醇提取物的体外抗氧化及抗炎活性[J].中国农业科学,2019,52(05):939-948.
学术著作
1. Dietary Polyphenols for Improving Gut Health: Volume 1, Kai Wang, Guiju Sun, Michael Allan Conlon, Guan Yang, Wenkai Ren, Frontiers Media SA, 2021, ISBN 2889717100
2. 神奇的无刺蜂 / (瑞士) 克里斯托弗·格鲁特著;王凯译著. --北京：中国农业科学技术出版社，2022.12，ISBN 978-7-5116-6059-6
3. 高效健康养蜂全程实操图解/张中印，吴黎明主编.北京：中国农业出版社，2018.07（副主编）
4. 蜂胶研究/胡福良等著.杭州：浙江大学出版社，2019.05（参编，第七章）
授权发明专利
1. 一种无刺蜂蜂蜜提取物及其提取方法和应用， ZL201810750208.3，王凯，吴黎明，梁馨文，薛晓锋，2019年
2. 无刺蜂蜂蜜多酚物质的提取及其在免疫调节中的应用，ZL201710696882.3，王凯，梁馨文，王亮，吴黎明，薛晓锋，2019年
3. 一种鉴别蜂花粉来源的方法，ZL201810565236.8，王凯，李强强，吴黎明，薛晓锋，2020年
4. 一种快速分析蜂花粉中脂类成分的方法，ZL201710415148.5，王凯，李强强，吴黎明，薛晓锋，2020年 （已转让）
5. 一种宠物用牙膏及其制备方法，ZL201710675356.9,王凯，吴黎明，薛晓锋，2020年
6. 一种夏枯草蜂蜜的鉴别方法，ZL201810643017.7，王凯，吴黎明，梁馨文，薛晓锋，2021年
7. 一种成熟油菜蜂蜜的鉴别方法，ZL20201017745.2Z，王凯，吴黎明，彭文君，赵柳微，郭娜娜，薛晓锋，2022年
8. 一种宠物护爪膏及其制备方法与应用，ZL202010941083.X，王凯，吴黎明，薛晓锋，2022年
9. 一种红花蜂蜜及含有红花蜂蜜的制品的检测方法，ZL201911203963.0，王凯，赵柳微，郭娜娜，薛晓锋，吴黎明，2022年
更新时间：2023-09-05
Curriculum Vitae
Kai Wang, Ph.D., Associate Professor
Research Scientist of Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.
Email: kaiwang628@gmail.com; wangkai@caas.cn
ORCID: 0000-0003-0553-5293
Scopus ID: 57203735794
Dr. Kai Wang is currently an Associate Professor from Institute of Apicultural Research, Chinese Academy of Agricultural Science, China. He earned his PhD in Agriculture (2016) from the Zhejiang University (China) studying the effects of bee propolis on inflammatory diseases and inflammatory microenvironment under the supervision of Professor Fuliang Hu. During his PhD studies (2015-16), he was sponsored by the China Scholarship Council (CSC) to conduct joint training at the Commonwealth Scientific and Industrial Research Organisation, CSIRO, in Australia, under the mentorships of Professor David Topping (Chief Research Scientist of CSIRO, FTSE, FNSA, MAIFST) and Dr. Michael Conlon (Senior Research Scientist of CSIRO). Dr Wang joined Institute of Apicultural Research, Chinese Academy of Agricultural science 2016. He was named an NSFC Excellent Young Scientist in 2023 and a recipient of the Beijing Nova Program in 2022, making him the only one in the discipline of Apiculture Sciences in China.
His researches major focused on “honey bees and bee products”, research interests include:
1. Exploring the mechanism of honey bee subhealth risk factors on honey bee production, and proposing the method of regulating bee colony immunity for prevention and control on diseases.
2. Analyzing the honey ripening mechanism of honey bees and establish the identification on different monofloral honeys.
3. Revealing the regulatory mechanism of propolis on the intestinal inflammatory microenvironment and elucidated the material basis in the bee propolis.
Dr Wang has published over 105 peer-reviewed publications in top journals with an H index of 36 (total citations= 4067, Google Scholar) and 32 (total citations = 3242, Scopus), 3 book chapters and 4 books. He was featured among the World's Top 2% Scientists List created by Stanford University (2022). He was also invited to be reviewers for more than 50 WoS-indexed journals and completed 172 peer reviews.
Dr Wang has served as editors for several different journals, including BMC Complementary Medicine and Therapies, Nutrients, Frontiers journals (Nutrition, Veterinary Science), and Plos One.
Updated on: 2023-09-05