李强强，博士，硕士生导师，副研究员。加拿大阿尔伯塔大学联合培养博士。现为中国农业科学院蜜蜂研究所蜂产品质量与风险评估创新团队科研骨干，主要从事农产品质量安全与营养功能研究。近年来主持国家自然科学基金青年基金项目、中国农业科学院“青年创新”专项、中央级公益性行业科研专项，并参与“十四五”国家重点研发专项、海南省重点研发专项等多项课题。以第一/通讯作者在《Journal of Advanced Research》、《Environment International》、《Food Chemistry》、《Journal of Agricultural & Food Chemistry》等期刊发表SCI论文30余篇，累计影响因子168.9，并获授权国家发明专利10项，参编著作1部。兼任中国养蜂学会理事，并长期担任多本国际SCI期刊客座编辑和审稿人。
Email: liqiangqiang@caas.cn
代表性课题（主持）：
国家自然科学基金青年基金项目，“蜂花粉采集和蜂粮酿制中致敏蛋白的酶促降解与发酵转化机制（32102605）”，2022年1月至2024年12月。
中国农业科学院“青年创新”专项，“膳食多酚共价修饰降低蜂花粉中过敏原致敏性的构效机制研究（Y2024QC11）”，2024年1月至2026年12月。
中央级公益性行业科研专项，“不同发育形态黄粉虫的蛋白质品质评价”，2023年1月至2023年12月。
中央级公益性行业科研专项，“油菜蜂花粉致敏蛋白的微生物发酵降解机制”，2022年1月至2022年12月。
近五年代表性论文（仅第一作者或通讯作者）：
Tan, S., Li, Q., Guo, C., Chen, S., Kamal-Eldin, A., & Chen, G. (2024). Reveal the mechanism of hepatic oxidative stress in mice induced by photo-oxidation milk using multi-omics analysis techniques. Journal of Advanced Research. https://doi.org/10.1016/j.jare.2024.07.005
Zhou, E., Li, Q., Xu, R., Pan, F., Tao, Y., Li, X., ... & Wu, L. (2024). Covalent conjugation with quercetin mitigates allergenicity of the bee pollen allergen Bra c p in a murine model. Food Chemistry, 436, 137722.
Yin, S., Li, Q., Tao, Y., Zhou, E., Wang, K., Chen, W., ... & Wu, L. (2024). Allergen degradation of bee pollen by lactic acid bacteria fermentation and its alleviatory effects on allergic reactions in BALB/c mice. Food Science and Human Wellness, 13(1), 349-359.
Zhou, E., Li, Q., Zhu, D., Chen, G., & Wu, L. (2024). Characterization of physicochemical and immunogenic properties of allergenic proteins altered by food processing: a review. Food Science and Human Wellness, 13(3), 1135-1151.
Zhou, E., Wang, W., Xue, X., Wang, P., Wu, F., Wu, L., & Li, Q. (2023). Hydrogen peroxide oxidation modifies the structural properties and allergenicity of the bee pollen allergen profilin. Food Chemistry, 425, 136495.
Zhao, T., Zhao, L., Wang, M., Qi, S., Xue, X., Wu, L., & Li, Q. (2023). Identification of characteristic markers for monofloral honey of Astragalus membranaceus var. mongholicus Hsiao: A combined untargeted and targeted MS-based study. Food chemistry, 404, 134312.
Zhou, E., Xue, X., Xu, H., Zhao, L., Wu, L., & Li, Q. (2023). Effects of covalent conjugation with quercetin and its glycosides on the structure and allergenicity of Bra cp from bee pollen. Food Chemistry, 406, 135075.
Ren, C., Li, Q., Luo, T., Betti, M., Wang, M., Qi, S., ... & Zhao, L. (2023). Antioxidant Polyphenols from Lespedeza bicolor Turcz. Honey: Anti-Inflammatory Effects on Lipopolysaccharide-Treated RAW 264.7 Macrophages. Antioxidants, 12(10), 1809.
Tao, Y., Yin, S., Fu, L., Wang, M., Meng, L., Li, F., ... & Li, Q. (2022). Identification of allergens and allergen hydrolysates by proteomics and metabolomics: A comparative study of natural and enzymolytic bee pollen. Food Research International, 158, 111572.
Li, Q., Zhang, W., Zhou, E., Tao, Y., Wang, M., Qi, S., ... & Wu, L. (2023). Integrated microbiomic and metabolomic analyses reveal the mechanisms by which bee pollen and royal jelly lipid extracts ameliorate colitis in mice. Food Research International, 171, 113069.
Li, Q., Xue, X., Qi, S., Zhao, L., Zhang, W., Fan, M., ... & Wang, M. (2022). Disinfectant dodecyl dimethyl benzyl ammonium chloride (DDBAC) disrupts gut microbiota, phospholipids, and calcium signaling in honeybees (Apis mellifera) at an environmentally relevant level. Environment International, 170, 107639.
Li, Q., Chen, G., Zhu, D., Zhang, W., Qi, S., Xue, X., ... & Wu, L. (2022). Effects of dietary phosphatidylcholine and sphingomyelin on DSS-induced colitis by regulating metabolism and gut microbiota in mice. The Journal of Nutritional Biochemistry, 105, 109004.
Li, Q., Ren, C., Yan, S., Wang, K., Hrynets, Y., Xiang, L., ... & Wu, L. (2021). Extract of Unifloral Camellia sinensis L. pollen collected by Apis mellifera L. honeybees exerted inhibitory effects on glucose uptake and transport by interacting with glucose transporters in human intestinal cells. Journal of Agricultural & Food Chemistry, 69(6), 1877-1887.
Li, Q., Liang, X., Xue, X., Wang, K., & Wu, L. (2019). Lipidomics provides novel insights into understanding the bee pollen lipids transepithelial transport and metabolism in human intestinal cells. Journal of Agricultural & Food Chemistry, 68(3), 907-917.
Li, Q., Sun, M., Wan, Z., Liang, J., Betti, M., Hrynets, Y., ... & Wang, K. (2019). Bee pollen extracts modulate serum metabolism in lipopolysaccharide-induced acute lung injury mice with anti-inflammatory effects. Journal of Agricultural & Food Chemistry, 67(28), 7855-7868.
Li, Q., Liang, X., Guo, N., Hu, L., Wu, Y., Xue, X., ... & Wang, K. (2019). Protective effects of Bee pollen extract on the Caco-2 intestinal barrier dysfunctions induced by dextran sulfate sodium. Biomedicine & Pharmacotherapy, 117, 109200.
授权发明专利（第一完成人）：
一种蜂花粉脂提物及其提取方法（ZL202010935704.3）
一种评价天然蜂花粉与酶法破壁蜂花粉致敏性的方法（ZL202110894683.X）
一种蜂花粉致敏蛋白的鉴定方法及应用（ZL202110732923.6）
一种评估天然蜂花粉及发酵蜂花粉致敏性的方法（ZL202110733122.1）
编著：
《Quality Evaluation of Bee Products》, 2023年12月，ISBN978-3-0365-9619-8